Publications, Conferences, & Articles

PathIntegrate: Multivariate Modelling Approaches for Pathway-Based Multi-Omics Data Integration

Published in PLOS Computational Biology, 2024

I contributed to the development of the PyPi PathIntegrate Python package (included in v1.0.0), a tool for pathway-based multi-omics data integration used in this publication. My contribution has a seperate doi but it is based on this paper from PLOS.

GitHub Repository: https://github.com/cwieder/PathIntegrate

Citation: Popham, J., Wieder, C., & Ebbels, T. (2024). cwieder/PathIntegrate: PathIntegrate Unsupervised (v1.0.0). Zenodo. --> 'Wieder C, Cooke J, Frainay C, et al. (2024). PathIntegrate: Multivariate Modelling Approaches for Pathway-Based Multi-Omics Data Integration. PLOS Computational Biology. 20(3): e1011814. doi:10.1371/journal.pcbi.1011814.
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Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes

Published in Circulation Research, 2023

I was a co-author for this publication, working on the single-cell component. This study provides a comprehensive proteomics analysis of human atherosclerotic plaques, revealing sex differences and distinct plaque phenotypes with prognostic implications.

GitHub Repository: https://github.com/Cardiovascular-Bioinformatics/Plaques_Cellular_Composition

Citation: Theofilatos K, Stojkovic S, Hasman M, Popham J, et al. (2023). "Proteomic Atlas of Atherosclerosis: The Contribution of Proteoglycans to Sex Differences, Plaque Phenotypes, and Outcomes." Circulation Research. 133(7):542-558. doi:10.1161/CIRCRESAHA.123.322590.
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Spatial Biology Network KCL

Invited to the Kings Spatial Biology Research Conference, 2024

This conference was focused on pilot studied with revolutionary CosMX Nanostring Spatial RNA-Seq data. All research groups, including ours, were working within the KCL Spatial Biology Network. Click the title to see an image of our presentation.

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MarketsAndMarkets 2nd Annual Single Cell-Omics Conference

Invited to the MarketsAndMarkets Conference, 2023

This conference discussed various Single-Cell RNA-Seq platforms available and emerging Single-Cell research in the field.

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Novel Plastic Degrading Enzymes

Published in KCL Biochemist Print, 2022

This article was inspired by the work of Professor Zelesniak who studied plastic degrading enzymes. It covers key processes of bioremediation and the potential of these enzymes for efficient recycling.

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The Science and Economics of Cannabis: A Case Study of Thailand

Published in Kings Business Review, 2022

This article is about the economic impact of cannabis in Thailand, also considering the scientific effects of cannabis on the brain and body. Please click the title if you want to have a read.

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Alternative Splicing and Neurogenesis

Published in KCL Biochemist Print, 2021

This article was inspired by the work of Professor Eugene Makeyev who studied intricate processes of gene expression regulation, such as NMD, during neurogenesis. My interest in this biological problem inspired my first bioinformatics internship which kickstarted my journey in the field today

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